Investigation of yeast and Drosophila ARF proteins and their associated GEFs expressed in Saccharomyces cerevisiae

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Title: Investigation of yeast and Drosophila ARF proteins and their associated GEFs expressed in Saccharomyces cerevisiae
Authors: Buchwald, Ulf
Thesis advisor: Prof. Dr. Jürgen J. Heinisch
Thesis referee: Prof. Dr. Achim Paululat
Abstract: The ADP-ribosylation factor (ARF) family of small G-proteins regulates membrane dynamics and intracellular membrane traffic. ARFs are activated upon GTP-binding catalyzed by guanine-nucleotide exchange factors (GEF), which works as a molecular switch and triggers association with specific target membranes. This work focused on the cloning, expression and characterization of genes from the milk yeast K. lactis and the fly D. melanogaster, which are putative homologs of the S. cerevisiae genes GEA1, GEA2, ARF1, ARF2, and ARF3.
URL: https://osnadocs.ub.uni-osnabrueck.de/handle/urn:nbn:de:gbv:700-201101177664
Subject Keywords: Yeast; Drosophila; ARF; GEF; Proteins
Issue Date: 17-Jan-2011
Type of publication: Dissertation oder Habilitation [doctoralThesis]
Appears in Collections:FB05 - E-Dissertationen

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